Pharmacotherapy (Part1 and Part2) Exam (BPS-Pharmacotherapy) Free Practice Test

Question 1

A patient with a COPD exacerbation is treated with prednisone 40 mg daily for one week with improvement. To discontinue the prednisone, the most appropriate procedure would be which of the following?

A. Reducing the daily prednisone dose by 50% every day until the patient is off the drug.

B. Reducing the daily prednisone dose by 25% every day until the patient is off the drug.

C. Reducing the daily prednisone dose by 50% every other day until it is down to 10 mg daily, then reducing it by 25% every other day until the patient is off the drug.

D. Stopping prednisone administration without dose tapering.

Correct Answer: D

Question 2

A pharmacotherapy specialist is evaluating a study that compared the effects of iron sucrose versus sodium ferric gluconate on ferritin levels in patients receiving hemodialysis. A significant difference was found between the groups. This study was conducted in a large academic center in Denmark; the specialist practices at a small rural hospital in Minnesota. Which of the following information in the paper will be most important in determining whether the study's results can be applied to the specialist's practice?

A. Randomization methods

B. Inclusion/exclusion criteria

C. Statistical analysis

D. Internal validity

Correct Answer: B

Question 3

In a clinical trial, when would "intention to treat" analysis be most appropriate?

A. Small sample size

B. Crossover design

C. High drop-out rate

D. Phase || trial

Correct Answer: A

Question 4

A postmenopausal patient with osteoporosis is being switched from conjugated estrogen to raloxifene treatment. Which of the following should be communicated to this patient as the best outcome that has been documented with raloxifene?

A. Decreased incidence of cardiovascular events

B. Lower likelihood of thromboembolic events

C. Decreased incidence of Vertebral fractures

D. Decreased incidence of hot flushes

Correct Answer: D

Question 5

A 67-year-old patient is hospitalized for decompensated heart failure. The serum sodium concentration is 130 mEq/L on admission. Which of the following is the most appropriate approach to managing the patient's hyponatremia?

A. Restriction of both sodium and fluids

B. 3% NaCl 50 mL/h intravenously for 5 hours

C. 0.9% NaCl 200 mL/h intravenously for 5 hours

D. Conivaptan 20 mg intravenously over 24 hours

Correct Answer: A

Question 6

A 25-year-old man who weighs 80 kg is brought to the emergency department following a motor vehicle collision. He has severe facial contusions and a presumed closed head injury. His Glasgow Coma Scale score is 8. An emergency CT scan shows no evidence of intracranial bleeding. What should recommendations for therapy include?

A. Phenytoin 1,200 mg intravenously over 45 minutes, then an appropriate maintenance dose for one week

B. Diazepam 5 mg intravenously over 5 minutes, qh6 for one week

C. Dexamethasone 10 mg intravenously q6h for one week

D. Fosphenytoin 25 PE/kg intravenous push, then an appropriate maintenance dose for one week

Correct Answer: C

Question 7

A MEDLINE search fails to retrieve a clinical trial known by the searcher to have been published in a recently established open-access medical journal. This failure has most likely occurred because of which of the following?

A. MEDLINE does not index open-access journals.

B. The time that the journal has been available does not meet criteria for indexing.

C. The searcher limited the search to "humans" and "English language."

D. MEDLINE selectively indexes articles of the highest scientific merit.

Correct Answer: B

Question 8

A 58-year-old man presents with symptoms of the common cold (nasal congestion, headaches, and dry Cough).
He purchased XYZ Cold formula (acetaminophen, pseudoephedrine, and dextromethorphan), but after reading the cautionary information on the package, he thought he should obtain his pharmacist's advice. He has hypertension and is taking hydrochlorothiazide daily. His office blood pressures range from 127-134/82-88 mm Hg, and he has no other medical problems.
Which of the following instructions are applicable to this patient regarding XYZ Cold formula?

A. Although pseudoephedrine is safe to use, he should use an antihistamine instead to better control his symptoms.

B. He should substitute nasal cromolyn for the decongestant.

C. He should avoid XYZ Cold because it significantly raises blood pressure.

D. XYZ Cold would be safe short term because he has well-controlled hypertension.

Correct Answer: D

Question 9

A 60-year-old man is admitted to the CCU with an acute anterior wall Ml. Therapy with amiodarone is initiated. The man's concurrent medications include Warfarin, furosemide, and enalapril. Which of the following baseline laboratory land clinical data, in addition to thyroid and liver function tests, should be obtained prior to initiation of amiodarone therapy in this patient?

A. Spirometry and 24-hour urine for creatinine clearance

B. Chest X-ray

C. Fasting blood glucose

D. FEV1 and baseline electroencephalogram

Correct Answer: D

Question 10

After 9 days of hospitalization, a 60-year-old 60-kg patient has a temperature of 39.4°C and a WBC count of 20,000 cells/uL. A sputum sample shows numerous WBCs and Gram-negative bacilli. The serum creatinine is 1.0 mg/dL. For this patient, which of the following drugs would be most appropriate for initial parenteral therapy?

A. Tobramycin and cefepime

B. Ceftriaxone and azithromycin

C. Cefepime, levofloxacin, and vancomycin

D. Aztreonam, clindamycin, and vancomycin

Correct Answer: A

Question 11

A patient presents a first-time prescription for exenatide subcutaneously twice daily. Which of the following information should the pharmacotherapy specialist present during patient counseling?

A. The drug should be taken within 60 minutes after eating the morning and evening meals.

B. Dose size should be adjusted according to the size of each meal.

C. The drug should be discarded 60 days after first use, even if some remains in the pen.

D. The most common side effect is nausea, which usually decreases over time.

Correct Answer: A

Question 12

A patient with previously well-controlled diabetes is suspected to be nonadherent with medication and diet. During the patient's last visit, the pharmacy student attempt to review education materials. However, the patient said that he forgot his reading glasses and asked if he could read through the information when he got home?
Which of the following is the best course of action for the patient at his next visit?

A. Ask the patient to read and interpret the instructions on a prescription label to evaluate literacy

B. Admit the patient to the hospital to optimize the diabetes regimen

C. Provider the patient with additional materials to read at home.

D. Ask the patient to follow up with his primary care provider.

Correct Answer: D

Question 13

The most efficient approach for comparing the efficacy of treatments for BPH is to search which of the following?

A. Cochrane Systematic Reviews

B. MEDLINE for clinical trials

C. Drug Facts & Comparisons

D. Lexicomp's Drug information Handbook

Correct Answer: B

Question 14

Which of the following is a risk factor for the development of multidrug resistance in pathogens that cause nosocomial pneumonia?

A. Hemodialysis initiated 2 days ago

B. Antimicrobial therapy implemented 6 months ago

C. Current hospitalization for the past 3 days

D. Home infusion therapy that includes antibiotics

Correct Answer: A

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BPS Pharmacotherapy (Part1 and Part2) (BPS-Pharmacotherapy) Free Practice Test