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Download ASCP : ASCP-MLT Questions & Answers as PDF & Test Software

Last Updated: Jun 06, 2026

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ASCP ASCP-MLT Practice Q&A's

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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. VLDL transports endogenous lipids, whereas chylomicrons transport exogenous (dietary) lipids. Cholesterol is transported by HDL and LDL.
The function of the very low density lipoproteins (VLDL) is to transport:

A) endogenous triglycerides
B) exogenous triglycerides
C) cholesterol and phospholipids to the peripheral cells
D) cholesterol from peripheral cells to the liver


2. The ApoB/ApoA1 ratio has a positive risk marker (ApoB-100) and a negative risk marker (ApoA1). Risk diminishes as ApoA1 goes up (a negative marker) and risk increases in proportion to ApoB concentrations (a positive risk marker). This 'double-edged sword' provides good risk prediction. The other risk markers in question do not have this dual-advantage.
Which risk marker has both positive and negative cardiovascular risk integrated into its measurement?

A) LpPLA2
B) hs-CRP
C) Oxidized LDL
D) ApoB/ApoA1


3. The presence of hyaline, septate hyphae, and a young conidiophore with a foot cell and a swollen vesicle in a fungus culture are excellent clues indicative of Aspergillus. Aspergillus has the ability to infect primarily immunocompromised hosts, and causes pneumonia and/or disseminates to other organs. Clinical specimens should be inoculated onto primary isolation media, such as Sabouraud's dextrose agar. Aspergillus spp. are fast growing and can be white, yellow, yellow-brown, brown to black or green in color.
The presence of hyaline, septate hyphae, and a young conidiophore with a foot cell and a swollen vesicle in a fungus culture are excellent clues indicative of:

A) Scopulariopsis
B) Aspergillus
C) Acremonium
D) Penicillium
E) Paecilomyces


4. Which of the following fields is NOT an aspect of clinical microbiology?

A) pathology
B) bacteriology
C) parasitology
D) virology


5. 21 CFR 606.65 states, "Supplies and reagents shall be used in a manner consistent with instructions provided by the manufacturer." The correct answer is A. The reagents must be used according to the manufacturer's instructions for use. If the instructions say one or two drops may be used and the facility procedures also allow one or two drops, then there is no problem with the staff members choosing to use two drops.
While equipment must be calibrated, it does not generally influence the number of drops used.
Staff members often ask co-workers and colleagues from other facilities how to perform tasks, but it is the manufacturer's instructions for the operation of equipment and the use of reagents that must be followed.
A laboratory employee who is performing an internal audit of routine ABO and Rh typing procedures notes that a technologist places two drops of Anti-D in a tube, centrifuges the tube for 20 seconds, and reads the reaction using a magnifying mirror. When questioned about the procedure, the technologist indicates that most staff use two drops of Anti-D reagent because the reactions are stronger with two drops. In addition to reviewing the facility procedure manual, what should be done to ensure regulatory compliance?

A) Review the anti-D manufacturer's current instructions for use.
B) Call a colleague at another institution to ask what they do.
C) Check the calibration records for the centrifuge.


Solutions:

Question # 1
Answer: A
Question # 2
Answer: D
Question # 3
Answer: B
Question # 4
Answer: A
Question # 5
Answer: A

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